TMEM107 and BIK

Data Source:
BioGRID (two hybrid)

		TMEM107	BIK
Description		transmembrane protein 107	BCL2 interacting killer
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Ciliary Transition Zone MKS Complex	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Detection Of Nodal Flow Regulation Of Gene Expression Neural Tube Patterning Embryonic Digit Morphogenesis Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)	Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		44 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35C2 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21	95 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBE2D1 UBIAD1 VAMP3 VAMP5 ZFPL1
Entrez ID		84314	638
HPRD ID		14400	04547
Ensembl ID		ENSG00000179029	ENSG00000100290
Uniprot IDs		Q6UX40	A0A024R4X6 Q13323
PDB IDs			2IPE
Enriched GO Terms of Interacting Partners?
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