LOXL4 and AP1M2

Data Source:
BioGRID (two hybrid)

		LOXL4	AP1M2
Description		lysyl oxidase like 4	adaptor related protein complex 1 subunit mu 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane Receptor Complex Extracellular Exosome	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein-lysine 6-oxidase Activity Scavenger Receptor Activity Copper Ion Binding Protein Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Endocytosis Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Collagen Fibril Organization	Protein Targeting Vesicle Targeting Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Elastic fibre formation Crosslinking of collagen fibrils	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Body mass index ( 29273807) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Height ( 31562340) Multiple system atrophy ( 27629089)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		15 interacting genes: AP1M2 APOE CDC37 COL2A1 ECSIT EXOC6 KDM1A LONP1 MAST1 MTDH PRMT6 RAD23A RNF32 SUV39H1 TRIP13	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		84171	10053
HPRD ID		09538	06296
Ensembl ID		ENSG00000138131	ENSG00000129354
Uniprot IDs		Q96JB6	Q53GI5 Q9Y6Q5
PDB IDs
Enriched GO Terms of Interacting Partners?
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