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BRIP1 and HNRNPC
Data Source:
BioGRID
(unspecified method)
BRIP1
HNRNPC
Description
BRCA1 interacting protein C-terminal helicase 1
heterogeneous nuclear ribonucleoprotein C
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Membrane
Chromatin
Extracellular Region
Nucleus
Nucleoplasm
Spliceosomal Complex
Telomerase Holoenzyme Complex
Cytosol
Actin Cytoskeleton
Membrane
Protein-containing Complex
Extracellular Exosome
Catalytic Step 2 Spliceosome
Molecular Function
DNA Binding
DNA Helicase Activity
Chromatin Binding
RNA Helicase Activity
Protein Binding
ATP Binding
Metal Ion Binding
4 Iron, 4 Sulfur Cluster Binding
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Poly(U) RNA Binding
Nucleosomal DNA Binding
Identical Protein Binding
Telomerase RNA Binding
N6-methyladenosine-containing RNA Binding
Biological Process
DNA Damage Checkpoint
DNA Replication
Nucleotide-excision Repair
Double-strand Break Repair
Regulation Of Transcription By RNA Polymerase II
Spermatogonial Cell Division
Spermatid Development
Negative Regulation Of Cell Population Proliferation
Response To Toxic Substance
Negative Regulation Of Gene Expression
Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination
DNA Duplex Unwinding
Chiasma Assembly
Cellular Response To Vitamin
Cellular Response To Hypoxia
Seminiferous Tubule Development
Regulation Of Signal Transduction By P53 Class Mediator
Cellular Response To Angiotensin
Double-strand Break Repair Involved In Meiotic Recombination
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
RNA Splicing
RNA Metabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
ATP-dependent Chromatin Remodeling
3'-UTR-mediated MRNA Stabilization
Pathways
Cytosolic iron-sulfur cluster assembly
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
SUMOylation of RNA binding proteins
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
Fanconi anemia
GWAS
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Ovarian cancer (
21964575
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Bipolar disorder (
31043756
21738484
)
Height (
31562340
)
Interacting Genes
10 interacting genes:
BLM
BRCA1
CREBBP
FANCD2
HDAC3
HNRNPC
HSD17B14
RPA1
SIRT1
TOPBP1
58 interacting genes:
AP1M1
BARD1
BRCA1
BRCA2
BRIP1
BTRC
CCDC85B
CDKN2A
CSNK1A1
CSNK2A1
CSNK2A2
DHX9
DISC1
EPS8
ERG
ESR1
FAS
FXR2
GRB2
HNRNPCL1
HNRNPCL2
IL7R
KHDRBS3
KPNA2
KPNA3
KPNA4
KPNA5
KRAS
LMO2
LMO3
MEOX2
PALB2
PAX6
PDGFB
PHKB
PIN1
PJA1
PRKDC
PTBP2
RAD51
RALY
RALYL
RBM41
RBPMS2
RNF4
SDCBP
SF3B2
SMARCD1
SREK1
SRPK2
SUMO1
SUMO1P1
TRAF3
UBE2I
YWHAE
YWHAQ
ZFYVE26
ZNF581
Entrez ID
83990
3183
HPRD ID
05797
01243
Ensembl ID
ENSG00000136492
ENSG00000092199
Uniprot IDs
Q9BX63
P07910
PDB IDs
1T15
1T29
3AL3
1TXP
1WF2
2MXY
2MZ1
3LN4
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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