L3MBTL2 and ZFY

Data Source:
BioGRID (two hybrid, two hybrid)

		L3MBTL2	ZFY
Description		L3MBTL histone methyl-lysine binding protein 2	zinc finger protein Y-linked
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Regulation Of Transcription By RNA Polymerase II
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs			3-Cyclohexyl-L-alanine PCL-016
Diseases
GWAS		Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		49 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829	4 interacting genes: DMRT3 KAT14 L3MBTL2 ZBTB9
Entrez ID		83746	7544
HPRD ID		13954	02466
Ensembl ID		ENSG00000100395	ENSG00000067646
Uniprot IDs		A0A0S2Z5X6 Q969R5	P08048
PDB IDs		2W0T 3CEY 3F70	1KLR 1KLS 1XRZ 5ZNF 7ZNF
Enriched GO Terms of Interacting Partners?
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