ABHD11 and VPS37C

Data Source:
BioGRID (two hybrid)

		ABHD11	VPS37C
Description		abhydrolase domain containing 11	VPS37C subunit of ESCRT-I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Mitochondrion	ESCRT I Complex Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome
	Molecular Function	Molecular_function Hydrolase Activity	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Biological_process	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Malaria ( 31844061) Total cholesterol levels ( 30498476)	Periventricular white matter hyperintensities ( 32517579) Rheumatoid arthritis ( 23143596)
Interacting Genes		22 interacting genes: ANKRD11 APP CSTF2 DOK6 DTX2 FNDC3B GCA MDFI MGAT5B MORN3 PITX1 PRKAB2 PROP1 PRR35 RUSC1 USHBP1 VAC14 VENTX VPS37C WWOX YTHDF1 ZIC1	102 interacting genes: AARD ABHD11 ABI2 APP ASCL3 BAG4 BIRC7 C1orf94 CBFA2T3 CEP55 CRX DAZAP2 DCTN3 DDIT3 DYDC1 EYA2 FAM168A FAM168B FCHSD2 FOXI1 FUBP1 GOLGA2 GPS2 GRB2 HAUS1 HELT HGS HNRNPF HNRNPUL1 HYI ILF3 KLF1 KRT27 KRT33B KRTAP15-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP7-1 LAGE3 LASP1 MAPK1IP1L METTL27 NTAQ1 NUP54 NUTM2F P4HA3 PAX9 PDCD6 PDCD6IP PEF1 PKNOX1 PKNOX2 PLA2G10 PLEKHG4 PLSCR1 POLR2J POLR2J3 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RAMAC RBPMS RBPMS2 RFX6 RIBC1 RINT1 RPRD1B RUNX1 SH3GL1 SH3RF1 SH3RF2 SORBS2 SORBS3 SPAG8 STAM2 STH TACC3 TFAP2D TFG TFIP11 TIAL1 TLE5 TSC1 TSG101 UBAP2 UBC UFSP1 VPS28 WWOX WWP2 XIAP YTHDF1 ZMAT5 ZMYND12 ZNF34
Entrez ID		83451	55048
HPRD ID		15658	15652
Ensembl ID		ENSG00000106077	ENSG00000167987
Uniprot IDs		C9J7Q4 D3DXF2 Q8NFV4	A5D8V6
PDB IDs
Enriched GO Terms of Interacting Partners?
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