UBL4A and USP13

Data Source:
BioGRID (enzymatic study)

		UBL4A	USP13
Description		ubiquitin like 4A	ubiquitin specific peptidase 13
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Chaperone Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Cellular Protein Modification Process Protein Phosphopantetheinylation Tail-anchored Membrane Protein Insertion Into ER Membrane	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Protein Phosphopantetheinylation Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)
Interacting Genes		14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 PER2 RNF126 S100P SEC61B SGTA SGTB TRAF4 TRIM54 USP13	18 interacting genes: AMFR BAG6 DAZAP2 DVL1 FNBP1L FUNDC2 LAPTM5 MCL1 MDC1 MRPL20 MYO15A SIAH2 SPRR2C TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		8266	8975
HPRD ID		02417	04666
Ensembl ID		ENSG00000102178	ENSG00000058056
Uniprot IDs		P11441	A0A0A6YZ17 Q92995
PDB IDs		2DZI 4WWR 4X86	2L80 2LBC
Enriched GO Terms of Interacting Partners?
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