SPACA1 and CACNG7

Data Source:
BioGRID (two hybrid)

		SPACA1	CACNG7
Description		sperm acrosome associated 1	calcium voltage-gated channel auxiliary subunit gamma 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Inner Acrosomal Membrane Acrosomal Membrane Integral Component Of Membrane	Early Endosome Plasma Membrane Voltage-gated Calcium Channel Complex AMPA Glutamate Receptor Complex Neuronal Cell Body Cerebellar Mossy Fiber Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Protein Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding Channel Regulator Activity
	Biological Process	Acrosome Assembly	Calcium Ion Transport Transmission Of Nerve Impulse Regulation Of MRNA Stability Positive Regulation Of Synaptic Transmission, Glutamatergic Cardiac Conduction Calcium Ion Transmembrane Transport Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Postsynaptic Neurotransmitter Receptor Diffusion Trapping Neurotransmitter Receptor Internalization Positive Regulation Of Dendrite Extension Regulation Of AMPA Receptor Activity
Pathways			Phase 0 - rapid depolarisation Phase 2 - plateau phase
Drugs			Ergocalciferol Enflurane Spironolactone Butamben Bioallethrin
Diseases
GWAS		Echocardiographic traits ( 17903301) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676)
Interacting Genes		25 interacting genes: AGPAT4 ATP6V0B ATP6V0C BNIP3 CACNG7 CD72 CLDN19 CTXN3 EMP1 EMP3 GIMAP5 LSMEM2 NRSN1 NSG1 PLN PMP22 RPRM SERP2 SERTM1 SGCG SMAGP SMIM3 THSD7B TMEM140 TMEM47	1 interacting genes: SPACA1
Entrez ID		81833	59284
HPRD ID		15419	06062
Ensembl ID		ENSG00000118434	ENSG00000105605
Uniprot IDs		Q9HBV2	P62955
PDB IDs
Enriched GO Terms of Interacting Partners?
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