CFHR5 and EBAG9

Data Source:
BioGRID (two hybrid)

		CFHR5	EBAG9
Description		complement factor H related 5	estrogen receptor binding site associated antigen 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Protein-containing Complex	Golgi Membrane Integral Component Of Membrane Secretory Granule
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Complement Activation, Alternative Pathway Regulation Of Complement Activation Negative Regulation Of Protein Binding Cytolysis By Host Of Symbiont Cells	Regulation Of Cell Growth Apoptotic Process
Pathways		Regulation of Complement cascade	Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Age-related macular degeneration (MTAG) ( 32277175) Asthma ( 29273806) Blood protein levels ( 29875488 28240269) Lupus nephritis in systemic lupus erythematosus ( 24925725) Matrix metalloproteinase-8 levels ( 29212897) Nephropathy ( 21399633)	Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
Interacting Genes		20 interacting genes: ARL13B C3 CISD2 CREB3 CREB3L1 EBAG9 ERGIC3 FFAR2 GPX8 KCNK7 LMNA MFSD14B PANX1 SLC10A1 SLC18A2 SLC4A1 STOM TMEM14B TMEM237 TMPRSS2	28 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB
Entrez ID		81494	9166
HPRD ID		06508	05775
Ensembl ID		ENSG00000134389	ENSG00000147654
Uniprot IDs		Q9BXR6	A0A024R9E0 O00559
PDB IDs
Enriched GO Terms of Interacting Partners?
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