FXR1 and BYSL

Data Source:
BioGRID (two hybrid)

		FXR1	BYSL
Description		FMR1 autosomal homolog 1	bystin like
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Skeletal Muscle Organ Development Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Population Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Signaling by BRAF and RAF fusions	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)	Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 20139978)
Interacting Genes		48 interacting genes: AP1M1 BLK BYSL C1orf35 CBX8 CCDC187 CDC7 CDKL3 CEP126 CRMP1 CSNK2A1 CWF19L2 CYFIP2 DHX15 ELOA ERCC6 ERG28 ESCO2 FAM161A FAM90A1 FBXO4 FMR1 FXR2 GBP2 HSPB1 KIF9 LNX1 LRIF1 LUC7L2 MAGOH MAGOHB MCRS1 MFAP1 PRAM1 PRPF31 PRSS23 SRPK2 STK16 SUFU SYT6 TBC1D22B TCEA2 TRPM1 YES1 ZMAT2 ZNF417 ZNF438 ZNF71	139 interacting genes: AIMP2 AMOTL2 APP ATP5F1B AXIN2 BEND7 BFSP1 BHLHE40 C1orf94 CAVIN4 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EAPP EMD EPS8 FAM228A FAM9B FCHO1 FXR1 FXR2 GAS8 GMCL1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 IKZF3 JRK KATNAL1 KIFC3 KLHL2 KLHL6 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LDOC1 LHX3 LMNA LMO1 LMO2 LONRF1 LTV1 LZTS1 LZTS2 MB21D2 MCIDAS MEOX1 MEOX2 MID1 MID2 MIPOL1 MKRN1 MRFAP1L1 MTUS2 NECAB2 NF2 OLIG3 OSBPL3 PDE4DIP PHC2 PICK1 PIH1D1 PNMA1 PNMA2 PRICKLE1 PSMC6 RACGAP1 RACK1 RALY RALYL RBAK RP9 RUBCN SMN1 SMN2 SNW1 SSX2IP STX11 TBC1D26 TEKT1 TFIP11 THAP1 TLE5 TNIP1 TRAF2 TRAF4 TRAK1 TRIM14 TRIM27 TRIM37 TRIM38 TRIM41 TRIM54 TRIM55 TRIP6 TRO TROAP UBE2H USH1G VIM VPS37B VPS52 WASF3 WTAP ZBTB14 ZBTB8A ZC2HC1C ZFP64 ZMAT5 ZNF212 ZNF286A ZNF426 ZNF438 ZNF48 ZNF655 ZNF668 ZNF71 ZNF835 ZRANB1 ZSCAN22
Entrez ID		8087	705
HPRD ID		02892	04848
Ensembl ID		ENSG00000114416	ENSG00000112578
Uniprot IDs		A0A0F7KYT8 A0A0F7L1S3 P51114	Q13895
PDB IDs		2CPQ 3KUF 3O8V	6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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