APOL3 and TNFRSF10D

Data Source:
BioGRID (two hybrid)

		APOL3	TNFRSF10D
Description		apolipoprotein L3	TNF receptor superfamily member 10d
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Lipid Transporter Activity Lipid Binding	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding
	Biological Process	Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Migration
Pathways			Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Estimated glomerular filtration rate ( 31152163) Total intracranial volume ( 31530798)	Attention deficit hyperactivity disorder ( 20732625) Lymphocyte percentage of white cells ( 32888494)
Interacting Genes		28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D	28 interacting genes: APOL3 ARFIP1 CIAO2A ECPAS FAM114A1 GAD2 HSBP1L1 INPP5K LAT MIEF1 MTERF4 PCYT1A PITPNC1 PLPP6 POLL RBP1 RMDN2 SEMA4G SENP2 SLC39A7 SUCLA2 TARS2 TBRG4 THAP4 TNFRSF10A TNFRSF10B TNFSF10 TUFM
Entrez ID		80833	8793
HPRD ID		06264	04682
Ensembl ID		ENSG00000128284	ENSG00000173530
Uniprot IDs		A0A024R1G6 O95236	Q9UBN6
PDB IDs
Enriched GO Terms of Interacting Partners?
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