EPC1 and HOPX

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EPC1	HOPX
Description		enhancer of polycomb homolog 1	HOP homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle	Chromatin Nucleus Cytoplasm
	Molecular Function	Histone Acetyltransferase Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition	Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation Chaperone-mediated Protein Complex Assembly
Pathways		HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Sexual dysfunction (female) ( 22509378)	Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic sclerosis ( 30247649)
Interacting Genes		9 interacting genes: CHRM5 E2F6 HOPX KAT5 KRT15 MBTD1 RINT1 SYCE1L TRIM27	9 interacting genes: EPC1 HDAC2 HOXB9 PICK1 PTGER4 SRF TCF12 TLX3 ZSCAN1
Entrez ID		80314	84525
HPRD ID		09941	06280
Ensembl ID		ENSG00000120616	ENSG00000171476
Uniprot IDs		Q9H2F5	Q9BPY8
PDB IDs		6NFX
Enriched GO Terms of Interacting Partners?
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