Wiki-Pi
About
Search
Browse
People
Updates
Search
ORAI2 and UNC119
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ORAI2
UNC119
Description
ORAI calcium release-activated calcium modulator 2
unc-119 lipid binding chaperone
Image
No pdb structure
GO Annotations
Cellular Component
Membrane
Integral Component Of Membrane
Growth Cone
Spindle Pole
Centrosome
Cytosol
Intercellular Bridge
Synapse
Spindle Midzone
Molecular Function
Protein Binding
Store-operated Calcium Channel Activity
Protein Binding
Lipid Binding
Biological Process
Store-operated Calcium Entry
Calcium Ion Transmembrane Transport
Mitotic Cytokinesis
Endocytosis
Chemical Synaptic Transmission
Nervous System Development
Visual Perception
Phototransduction
Lipoprotein Transport
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Elevation of cytosolic Ca2+ levels
Ion homeostasis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Chronotype (
30696823
27494321
)
Morning vs. evening chronotype (
27494321
)
Interacting Genes
5 interacting genes:
COPS6
GDF9
MED31
SETDB1
UNC119
103 interacting genes:
AAGAB
ALDH2
AMOT
ANKRD24
ANXA1
ANXA3
ANXA7
ARL15
ARL2
ARL3
ARL4D
ASH2L
BCR
BRIX1
BTBD2
C16orf74
CBX8
CCL18
CD247
CD3E
CD4
CDC42
CDKN1A
CDKN2C
CETN3
CKMT2
CKS2
COX17
CYB561D2
EIF2S2
ERH
FKBPL
FXYD6
FYN
GIPC2
GSTM4
HCK
HLA-DQA1
HMGB1
HSPB3
HSPE1
ID2
IL5RA
ITSN1
KDM1A
KRTAP1-3
KRTAP9-3
KRTAP9-8
LAMA4
LCK
LIG4
LRIF1
LUC7L2
LYN
MAP3K20
MAPK10
MAPK8IP2
MPHOSPH6
MRPS12
ORAI2
PAFAH1B3
PAPSS1
PCDHA4
PFN1
PHF10
PIN1
PLPP2
PPA1
PPP3CA
PPP3CC
PSMD11
PSMD2
PTPRS
QTRT1
RAP1B
RASSF6
RBPMS2
RCAN3
RCC1
RFC5
RGL2
RPA2
RPS6KA5
RUFY3
S100A4
S100A8
SAT1
SEPHS1
SERPINB9
SMN1
SULT1E1
TK1
TMEM200A
TP53BP2
TP53I3
TP53INP1
TRDMT1
TSC22D1
UBE2B
UBE2I
UBQLN4
ZFP64
ZNF24
Entrez ID
80228
9094
HPRD ID
09860
04927
Ensembl ID
ENSG00000160991
ENSG00000109103
Uniprot IDs
B4DUB4
Q96SN7
K7EN86
Q13432
PDB IDs
3GQQ
3RBQ
4GOJ
4GOK
5L7K
6H6A
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?