TMEM62 and LTA4H

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TMEM62	LTA4H
Description		transmembrane protein 62	leukotriene A4 hydrolase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Nucleus Nucleoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Hydrolase Activity	RNA Binding Aminopeptidase Activity Epoxide Hydrolase Activity Leukotriene-A4 Hydrolase Activity Protein Binding Peptidase Activity Zinc Ion Binding Tripeptide Aminopeptidase Activity Metalloaminopeptidase Activity
	Biological Process		Proteolysis Leukotriene Metabolic Process Leukotriene Biosynthetic Process Long-chain Fatty Acid Biosynthetic Process Peptide Catabolic Process Neutrophil Degranulation Cellular Protein Metabolic Process
Pathways			Synthesis of Leukotrienes (LT) and Eoxins (EX) Neutrophil degranulation Biosynthesis of D-series resolvins Biosynthesis of protectins Biosynthesis of E-series 18(S)-resolvins Biosynthesis of aspirin-triggered D-series resolvins Biosynthesis of E-series 18(R)-resolvins
Drugs			Captopril N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine 3-(Benzyloxy)Pyridin-2-Amine Imidazole Ubenimex DG051 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole N-(pyridin-3-ylmethyl)aniline (4-fluorophenyl)(pyridin-4-yl)methanone 1-(2,2'-bithiophen-5-yl)methanamine N-[4-(benzyloxy)phenyl]glycinamide (2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid 4-amino-N-[4-(benzyloxy)phenyl]butanamide N-methyl-1-(2-thiophen-2-ylphenyl)methanamine {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol 1-(4-thiophen-2-ylphenyl)methanamine N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline 4-(2-amino-1,3-thiazol-4-yl)phenol Kelatorphan 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol Tosedostat
Diseases
GWAS			Blood protein levels ( 30072576) Diffusing capacity of carbon monoxide ( 30694715) Height ( 20966902) Refractive error ( 32231278) Small intestine neuroendocrine tumor ( 27492634) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		8 interacting genes: APEH CSE1L F2RL1 HSPA5 LTA4H PTPN6 SLC27A6 ZNF287	3 interacting genes: ARPC3 TINF2 TMEM62
Entrez ID		80021	4048
HPRD ID		08669	01056
Ensembl ID		ENSG00000137842	ENSG00000111144
Uniprot IDs		Q0P6H9	A0A140VK27 P09960
PDB IDs			1GW6 1H19 1HS6 1SQM 2R59 2VJ8 3B7R 3B7S 3B7T 3B7U 3CHO 3CHP 3CHQ 3CHR 3CHS 3FH5 3FH7 3FH8 3FHE 3FTS 3FTU 3FTV 3FTW 3FTX 3FTY 3FTZ 3FU0 3FU3 3FU5 3FU6 3FUD 3FUE 3FUF 3FUH 3FUI 3FUJ 3FUK 3FUL 3FUM 3FUN 3U9W 4DPR 4L2L 4MKT 4MS6 4R7L 4RSY 4RVB 5AEN 5BPP 5FWQ 5N3W 5NI2 5NI4 5NI6 5NIA 5NID 5NIE 6ENB 6ENC 6END 6O5H
Enriched GO Terms of Interacting Partners?
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