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GSDMD and KCTD6
Data Source:
BioGRID
(two hybrid, two hybrid)
GSDMD
KCTD6
Description
gasdermin D
potassium channel tetramerization domain containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleoplasm
Cytosol
Plasma Membrane
Integral Component Of Membrane
Specific Granule Lumen
NLRP3 Inflammasome Complex
Tertiary Granule Lumen
Ficolin-1-rich Granule Lumen
Cytosol
M Band
Molecular Function
Phosphatidylserine Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol-4-phosphate Binding
Phosphatidic Acid Binding
Cardiolipin Binding
Protein Binding
Ankyrin Binding
Identical Protein Binding
Cullin Family Protein Binding
Biological Process
Inflammatory Response
Positive Regulation Of Interleukin-1 Beta Production
Pore Formation In Membrane Of Other Organism
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Pore Complex Assembly
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Protein Homooligomerization
Pyroptosis
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Regulation Of Growth
Post-translational Protein Modification
Negative Regulation Of Smoothened Signaling Pathway
Protein Homooligomerization
Pathways
Neutrophil degranulation
RUNX1 regulates estrogen receptor mediated transcription
Neddylation
Estrogen-dependent gene expression
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Schizophrenia (
31268507
)
Hepcidin/transferrin saturation ratio (
27846281
)
Refractive error (
32231278
)
Systemic lupus erythematosus (
28714469
)
vWF levels (
30586737
)
Interacting Genes
8 interacting genes:
ASPG
KCTD6
MEOX2
MFHAS1
PSMA1
ZBTB33
ZNF426
ZNF558
28 interacting genes:
ACTN1
ACTN3
ANK1
BAG4
C8orf33
CDC23
CTNND1
CUL3
EHHADH
ERBB2
FAM124B
GOLGA8EP
GOLGA8F
GRB7
GSDMD
LNX1
MOS
NTAQ1
PICK1
PPIG
PRPF31
PSMA1
REL
SDCBP
TBC1D2
TCEANC
TEPSIN
ZCCHC10
Entrez ID
79792
200845
HPRD ID
11014
13769
Ensembl ID
ENSG00000104518
ENSG00000168301
Uniprot IDs
P57764
Q8NC69
PDB IDs
5NH1
5WQT
6AO4
6KN0
6N9O
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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