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PALB2 and RAD51AP1
Data Source:
BioGRID
(pull down)
PALB2
RAD51AP1
Description
partner and localizer of BRCA2
RAD51 associated protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Protein-containing Complex
Molecular Function
DNA Binding
Protein Binding
DNA Secondary Structure Binding
DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
RNA Binding
Protein Binding
D-loop DNA Binding
Biological Process
Double-strand Break Repair Via Homologous Recombination
Somitogenesis
Inner Cell Mass Cell Proliferation
Mesoderm Development
Animal Organ Morphogenesis
Multicellular Organism Growth
Post-anal Tail Morphogenesis
Negative Regulation Of Apoptotic Process
Embryonic Organ Development
Double-strand Break Repair Via Homologous Recombination
DNA Repair
Cellular Response To DNA Damage Stimulus
Regulation Of Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
Meiotic Cell Cycle
Cellular Response To Ionizing Radiation
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
Fanconi anemia
GWAS
Bipolar disorder (
17554300
)
Colorectal cancer (
23263487
)
Phosphorus levels (
20558539
)
Interacting Genes
32 interacting genes:
BCAS3
BRCA2
CASZ1
CCL5
CST6
DIRAS3
ERRFI1
GREB1
H2BC3
H3C1
H4C1
HNRNPC
IL13RA2
IL24
KEAP1
KLK6
LRATD2
LYPD3
MRC2
NAT2
PDS5B
PRDM14
RAD51
RAD51AP1
RAD51C
RHOBTB2
RNF168
SERPINB5
SNAI1
THRSP
USP2
XRCC3
8 interacting genes:
APP
DMC1
LRRK2
MAP3K1
NEDD4
PALB2
RAD51
SIAH1
Entrez ID
79728
10635
HPRD ID
07966
04350
Ensembl ID
ENSG00000083093
ENSG00000111247
Uniprot IDs
H3BN63
Q86YC2
Q96B01
PDB IDs
2W18
3EU7
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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