GALNT12 and MUC2

Data Source:
HPRD (in vitro)

		GALNT12	MUC2
Description		polypeptide N-acetylgalactosaminyltransferase 12	mucin 2, oligomeric mucus/gel-forming
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Extracellular Space Golgi Lumen Plasma Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Inner Mucus Layer Outer Mucus Layer
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding	Protein Binding
	Biological Process	O-glycan Processing Protein Phosphopantetheinylation	Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Maintenance Of Gastrointestinal Epithelium
Pathways		Defective GALNT12 causes colorectal cancer 1 (CRCS1) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Asthma ( 31959851) Brain morphology (MOSTest) ( 32665545) FEV1 ( 30804560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)	Asthma ( 31361310 31959851 30929738 32296059) Asthma (adult onset) ( 30929738) Interstitial lung disease ( 23583980) Medication use (adrenergics, inhalants) ( 31015401)
Interacting Genes		16 interacting genes: APP BMPR1A BUB1 CDH1 CDKN2A FBXW7 MLH3 MSH2 MUC1 MUC2 MUC5AC MUC7 PIK3CA PMS2 RB1 SRC	4 interacting genes: GALNT12 GALNT14 MLH1 PLEKHM1
Entrez ID		79695	4583
HPRD ID		13561	11828
Ensembl ID		ENSG00000119514	ENSG00000198788
Uniprot IDs		Q8IXK2
PDB IDs		6PXU
Enriched GO Terms of Interacting Partners?
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