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BEND5 and EIF3D
Data Source:
BioGRID
(two hybrid)
BEND5
EIF3D
Description
BEN domain containing 5
eukaryotic translation initiation factor 3 subunit D
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Membrane
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
Molecular Function
DNA Binding
Protein Binding
RNA Binding
Translation Initiation Factor Activity
Protein Binding
MRNA Cap Binding
Biological Process
Negative Regulation Of Transcription, DNA-templated
Formation Of Cytoplasmic Translation Initiation Complex
Cap-dependent Translational Initiation
Translational Initiation
Positive Regulation Of Translation
IRES-dependent Viral Translational Initiation
Viral Translational Termination-reinitiation
Positive Regulation Of MRNA Binding
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes
27 interacting genes:
APP
BUD31
CTNNBIP1
DDR1
EIF3D
ERBB3
FAM161A
GFI1B
GORASP2
GRAP2
LCE1B
LMO3
NTAQ1
PIMREG
PRKAB2
PTGR2
RTP5
SMARCD1
TSPOAP1
UBE2I
USP2
USP20
USP7
VPS25
ZGPAT
ZNF417
ZNF688
31 interacting genes:
ANKRD28
BEND5
CCDC125
CCDC57
CDC42
CEP70
CREBBP
DNAJB11
DVL3
EIF3G
EIF3J
EIF3L
EIF5
ERCC6
GOLGA6L9
HOMER3
HOOK2
HSF2BP
KIFC3
LZTS2
MORN3
MTUS2
PHLDA1
PICK1
POLR2G
REL
SAT1
TFIP11
TRIM23
TRIM27
ZRANB1
Entrez ID
79656
8664
HPRD ID
07756
04888
Ensembl ID
ENSG00000162373
ENSG00000100353
Uniprot IDs
A0A0S2Z5N0
Q7L4P6
O15371
PDB IDs
6YBD
6YBS
6ZMW
6ZON
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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