CYBC1 and PEX12

Data Source:
BioGRID (two hybrid)

		CYBC1	PEX12
Description		cytochrome b-245 chaperone 1	peroxisomal biogenesis factor 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process	Innate Immune Response Respiratory Burst After Phagocytosis	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		64 interacting genes: ADIPOQ AGTRAP AHNAK2 AIG1 APCDD1L APOA2 APOL2 AQP10 AQP6 AQP8 BET1 C14orf180 C4orf3 CD53 CISD2 CLDN7 CLN6 COQ9 CPLX4 CREB3 CREB3L1 CYBB ERGIC3 ETS1 FAM209A GJA8 GPR151 GPR152 HSD17B11 HSD17B13 INSIG2 JAGN1 KASH5 KIR2DL3 LAT LMNA LXN MFF MFSD14B MGST3 MTIF3 NINJ2 NOX3 NRM P2RX1 PDZK1IP1 PEX12 PLIN3 PLP1 PLP2 SCD SHISA4 SLC35C2 SPN SSMEM1 STX2 THBD TM4SF19 TMEM128 TMEM80 TMPRSS2 TMX2 TRAM1L1 TSPAN12	36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA
Entrez ID		79415	5193
HPRD ID		14630	03455
Ensembl ID		ENSG00000178927	ENSG00000108733
Uniprot IDs		A0A024R8W9 Q9BQA9	O00623
PDB IDs
Enriched GO Terms of Interacting Partners?
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