PLEKHF1 and NPM2

Data Source:
BioGRID (two hybrid)

		PLEKHF1	NPM2
Description		pleckstrin homology and FYVE domain containing 1	nucleophosmin/nucleoplasmin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Lysosome Lysosomal Membrane Endosome Endosome Membrane Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Metal Ion Binding Phosphatidylinositol-4-phosphate Binding	Chromatin Binding RNA Binding Protein Binding Enzyme Binding Histone Binding Identical Protein Binding
	Biological Process	Apoptotic Process Endosome Organization Positive Regulation Of Autophagy Vesicle Organization Protein Localization To Plasma Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Blastocyst Development Chromatin Remodeling Regulation Of Exit From Mitosis Single Fertilization Oocyte Differentiation Positive Regulation Of Catalytic Activity Positive Regulation Of DNA Replication Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of DNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Obesity-related traits ( 23251661) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: CAVIN2 CHIC2 KIFBP L3MBTL3 NPM2 TNFAIP8 TNNT1	5 interacting genes: NPM1 PLEKHF1 PLEKHF2 SDCBP2 SRPK2
Entrez ID		79156	10361
HPRD ID		15146	12160
Ensembl ID		ENSG00000166289	ENSG00000158806
Uniprot IDs		B4DWN9 Q96S99	Q86SE8
PDB IDs			3T30
Enriched GO Terms of Interacting Partners?
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