CACNB1 and ATN1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CACNB1	ATN1
Description		calcium voltage-gated channel auxiliary subunit beta 1	atrophin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Sarcolemma Synapse	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Voltage-gated Calcium Channel Activity Protein Binding High Voltage-gated Calcium Channel Activity	RNA Polymerase II Transcription Factor Binding Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Chemical Synaptic Transmission Neuromuscular Junction Development Cardiac Conduction Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Cellular Response To Amyloid-beta	Negative Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Neuron Apoptotic Process
Pathways		Presynaptic depolarization and calcium channel opening NCAM1 interactions Phase 0 - rapid depolarisation Phase 2 - plateau phase	Regulation of PTEN gene transcription
Drugs		Ergocalciferol Enflurane Ranolazine Phenytoin Topiramate Ibutilide Amlodipine Nimodipine Spironolactone Magnesium sulfate Levomenthol Ethanol Miconazole Amiodarone Mibefradil Dronedarone Trimebutine Azelnidipine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases			Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Asthma ( 31619474) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)	Refractive error ( 32231278)
Interacting Genes		8 interacting genes: APP ATN1 CACNA1A CTBP2 DYNLL1 NEDD4L REM1 SRPK1	121 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PPP1R32 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SH3RF1 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 USP2 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZNF503 ZSWIM8
Entrez ID		782	1822
HPRD ID		11743	06311
Ensembl ID		ENSG00000067191	ENSG00000111676
Uniprot IDs		Q02641	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?
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