PRDM2 and TBCE

Data Source:
BioGRID (unspecified method)

		PRDM2	TBCE
Description		PR/SET domain 2	tubulin folding cofactor E
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus	Cytoplasm Microtubule
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Methyltransferase Activity Zinc Ion Binding Sequence-specific DNA Binding	Protein Binding Alpha-tubulin Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Determination Of Adult Lifespan Regulation Of Gene Expression Methylation Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Mitotic Spindle Organization
Pathways			Post-chaperonin tubulin folding pathway
Drugs
Diseases			Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome Kenny-Caffey syndrome
GWAS		Anti-drug antibodies in autoimmune disease (time to event) ( 33125391) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Copper levels ( 26025379) Intracranial aneurysm ( 30823506) Left ventricular function change in anthracycline treatment ( 28542097) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Parkinson's disease ( 26227905) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Refractive error ( 32231278)	Adiposity ( 19557161) Blood protein levels ( 30072576) Household income (MTAG) ( 31844048)
Interacting Genes		6 interacting genes: E2F1 ESR1 H3-4 H3C1 MDM2 RB1	2 interacting genes: TBCD TUBA4A
Entrez ID		7799	6905
HPRD ID		03120	05381
Ensembl ID		ENSG00000116731	ENSG00000284770
Uniprot IDs		Q13029	A0A2R8Y6Q1 Q15813
PDB IDs		2JV0 2QPW	4ICU 4ICV
Enriched GO Terms of Interacting Partners?
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