TBCE and TBCD

Data Source:
HPRD (in vitro)

		TBCE	TBCD
Description		tubulin folding cofactor E	tubulin folding cofactor D
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule	Cytoplasm Centrosome Microtubule Adherens Junction Bicellular Tight Junction Lateral Plasma Membrane
	Molecular Function	Protein Binding Alpha-tubulin Binding Chaperone Binding	GTPase Activator Activity Protein Binding Beta-tubulin Binding Chaperone Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Mitotic Spindle Organization	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Positive Regulation Of GTPase Activity Cell Morphogenesis Involved In Neuron Differentiation Bicellular Tight Junction Assembly
Pathways		Post-chaperonin tubulin folding pathway	Post-chaperonin tubulin folding pathway
Drugs
Diseases		Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome Kenny-Caffey syndrome
GWAS		Adiposity ( 19557161) Blood protein levels ( 30072576) Household income (MTAG) ( 31844048)	Blond vs. brown/black hair color ( 30531825) Bone mineral accretion in asthma (oral corticosteroid dose interaction) ( 26025128) Mean platelet volume ( 32888494) Moderate-to-late spontaneous preterm birth ( 31194736) Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309)
Interacting Genes		2 interacting genes: TBCD TUBA4A	13 interacting genes: ACD APP ARL2 DEXI MTDH MTNR1B POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6
Entrez ID		6905	6904
HPRD ID		05381	05227
Ensembl ID		ENSG00000284770	ENSG00000141556
Uniprot IDs		A0A2R8Y6Q1 Q15813	Q9BTW9
PDB IDs		4ICU 4ICV
Enriched GO Terms of Interacting Partners?
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