EIF4H and LAT2

Data Source:
BioGRID (two hybrid)

		EIF4H	LAT2
Description		eukaryotic translation initiation factor 4H	linker for activation of T cells family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane Membrane Raft Extracellular Exosome
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding Cadherin Binding	Protein Binding SH2 Domain Binding
	Biological Process	Formation Of Translation Preinitiation Complex Translational Initiation Regulation Of Translational Initiation Viral Process Sexual Reproduction Developmental Growth Eukaryotic Translation Initiation Factor 4F Complex Assembly	Adaptive Immune Response Calcium-mediated Signaling Intracellular Signal Transduction Fc-epsilon Receptor Signaling Pathway B Cell Activation Mast Cell Degranulation B Cell Receptor Signaling Pathway
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization
Drugs
Diseases
GWAS			Systemic lupus erythematosus ( 29848360)
Interacting Genes		7 interacting genes: C11orf68 DDIT4L DLG3 FBXO17 LNX1 PICK1 SPG21	7 interacting genes: CBL GAB1 GRB2 PLCG1 PLCG2 SOS1 UBQLN4
Entrez ID		7458	7462
HPRD ID		11940	09304
Ensembl ID		ENSG00000106682	ENSG00000086730
Uniprot IDs		Q15056	Q9GZY6
PDB IDs			3MAZ
Enriched GO Terms of Interacting Partners?
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