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EIF4H and CCL24
Data Source:
BioGRID
(affinity chromatography technology)
EIF4H
CCL24
Description
eukaryotic translation initiation factor 4H
C-C motif chemokine ligand 24
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Membrane
Eukaryotic Translation Initiation Factor 4F Complex
Perinuclear Region Of Cytoplasm
Extracellular Space
Molecular Function
RNA Binding
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
RNA Strand Annealing Activity
RNA Strand-exchange Activity
Ribosomal Small Subunit Binding
Cadherin Binding
Protein Binding
Chemokine Activity
CCR3 Chemokine Receptor Binding
Receptor Ligand Activity
CCR Chemokine Receptor Binding
Biological Process
Formation Of Translation Preinitiation Complex
Translational Initiation
Regulation Of Translational Initiation
Viral Process
Sexual Reproduction
Developmental Growth
Eukaryotic Translation Initiation Factor 4F Complex Assembly
Positive Regulation Of Endothelial Cell Proliferation
Monocyte Chemotaxis
Chemotaxis
Inflammatory Response
Immune Response
Cytoskeleton Organization
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Regulation Of Cell Shape
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of GTPase Activity
Positive Regulation Of Angiogenesis
Eosinophil Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Inflammatory Response
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Eosinophil Migration
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
CCL24 levels (
25147954
)
Eosinophil counts (
32888494
27863252
)
Eosinophil percentage of granulocytes (
27863252
)
Eosinophil percentage of white cells (
32888494
27863252
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Sum eosinophil basophil counts (
27863252
)
Interacting Genes
7 interacting genes:
C11orf68
DDIT4L
DLG3
FBXO17
LNX1
PICK1
SPG21
6 interacting genes:
CCL13
CCL21
CCL5
CCR3
CXCL11
XCL1
Entrez ID
7458
6369
HPRD ID
11940
03931
Ensembl ID
ENSG00000106682
ENSG00000106178
Uniprot IDs
Q15056
O00175
PDB IDs
1EIG
1EIH
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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