VCAM1 and TRIM65

Data Source:
BioGRID (pull down)

		VCAM1	TRIM65
Description		vascular cell adhesion molecule 1	tripartite motif containing 65
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Sarcolemma Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex	Nucleoplasm Cytosol
	Molecular Function	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding	Zinc Ion Binding
	Biological Process	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Response To Lipopolysaccharide Heterotypic Cell-cell Adhesion Response To Nicotine Calcium-mediated Signaling Using Intracellular Calcium Source Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Regulation Of Immune Response Leukocyte Tethering Or Rolling Cell Chemotaxis Interferon-gamma-mediated Signaling Pathway Innervation Cardiac Neuron Differentiation Cellular Response To Tumor Necrosis Factor Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta	Positive Regulation Of Autophagy
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling
Drugs		Ethanol Carvedilol Succinobucol Clove oil
Diseases
GWAS		Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244 24076602 21833088) Neutrophil percentage of white cells ( 32888494) SjÃ¶gren's syndrome ( 24097067)	Body mass index ( 29273807) Deep white matter hyperintensities ( 32517579) Psoriasis ( 28537254) Reticulocyte count ( 32888494) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 21681796 25663218) White matter hyperintensity volume ( 30659137)
Interacting Genes		13 interacting genes: CCL17 CCL22 CTSG ELANE EZR IL13 ITGAD ITGB1 ITGB7 MSN TRIM54 TRIM65 USP2	12 interacting genes: ANAPC11 IFIH1 MARCHF7 MKRN3 RBCK1 SRPK1 TNRC6A UBE2D2 UBE2U UBE2Z UBE3A VCAM1
Entrez ID		7412	201292
HPRD ID		01888	15569
Ensembl ID		ENSG00000162692	ENSG00000141569
Uniprot IDs		P19320	Q6PJ69
PDB IDs		1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?
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