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VAV2 and CCNO
Data Source:
BioGRID
(two hybrid)
VAV2
CCNO
Description
vav guanine nucleotide exchange factor 2
cyclin O
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Cyclin-dependent Protein Kinase Holoenzyme Complex
Nucleus
Nucleolus
Cytoplasm
Cyclin A2-CDK2 Complex
Molecular Function
Phosphotyrosine Residue Binding
Guanyl-nucleotide Exchange Factor Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Metal Ion Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Biological Process
Angiogenesis
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Small GTPase Mediated Signal Transduction
Regulation Of Cell Size
Cell Migration
Lamellipodium Assembly
Platelet Activation
Fc-epsilon Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Apoptotic Process
Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Mitotic Cell Cycle
Response To Drug
Mitotic Cell Cycle Phase Transition
Cell Division
Cilium Assembly
Multi-ciliated Epithelial Cell Differentiation
Pathways
GPVI-mediated activation cascade
GPVI-mediated activation cascade
NRAGE signals death through JNK
Rho GTPase cycle
Regulation of actin dynamics for phagocytic cup formation
DAP12 signaling
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
EPH-ephrin mediated repulsion of cells
G alpha (12/13) signalling events
VEGFA-VEGFR2 Pathway
VEGFA-VEGFR2 Pathway
Signal transduction by L1
VEGFR2 mediated vascular permeability
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Central corneal thickness (
29760442
)
Corneal astigmatism (
30306274
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Multiple sclerosis (
20598377
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Red blood cell count (
32888494
)
vWF and FVIII levels (
21810271
)
Cocaine dependence (
31212010
)
Interacting Genes
66 interacting genes:
AR
ARIH1
BIRC6
BOD1L1
BRDT
BZW1
CAV1
CBL
CBLB
CCNO
CCT2
CCT3
CD19
CD44
CEP170
CHMP3
CRCP
DCUN1D4
DNAJC21
EGFR
EIF4G3
EPHB2
ERBB2
ERBB3
ERBB4
FNTA
FUCA1
FYN
GAB1
GAPVD1
GRB2
HNRNPF
HSPH1
IPO4
MED21
MET
MRGBP
NCKAP5
NEK3
PHF10
PNMA1
POGZ
PPM1B
PRLR
RAC1
RAD23A
RBBP6
RHOA
RHOG
SERBP1
SF3A3
SH3BP2
SNW1
SOCS1
SRPK2
SRRT
ST13
STK24
SYK
TARBP2
TCP11
TOM1L1
TTN
UBE4B
USP38
VCPIP1
6 interacting genes:
HSPB1
ITSN1
PCNA
RPA2
TLE5
VAV2
Entrez ID
7410
10309
HPRD ID
02694
06375
Ensembl ID
ENSG00000160293
ENSG00000152669
Uniprot IDs
P52735
P22674
PDB IDs
2DLZ
2DM1
2LNW
2LNX
4ROJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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