VPS51 and NUDT3

Data Source:
BioGRID (two hybrid)

		VPS51	NUDT3
Description		VPS51 subunit of GARP complex	nudix hydrolase 3
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GO Annotations	Cellular Component	GARP Complex Nucleolus Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome EARP Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity
	Biological Process	Lipid Transport Autophagy Golgi Organization Lysosomal Transport Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Brain Morphogenesis	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Inositol Phosphate Metabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		Retrograde transport at the Trans-Golgi-Network	Synthesis of pyrophosphates in the cytosol
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Serum uric acid levels ( 32514006)	Atrial fibrillation ( 29892015) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29381148 20935630) Diastolic blood pressure ( 30224653) Estimated glomerular filtration rate ( 30604766) Height ( 25429064 19893584 31562340) Hip circumference ( 25673412) Myeloproliferative neoplasms ( 33057200) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: CDKN1A GSK3B NUDT3 VPS54 YTHDC1	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		738	11165
HPRD ID		12605	14849
Ensembl ID		ENSG00000149823	ENSG00000272325
Uniprot IDs		Q9UID3	O95989
PDB IDs		4J2C	2FVV 2Q9P 6PCK 6PCL
Enriched GO Terms of Interacting Partners?
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