UGCG and RTN3

Data Source:
HPRD (two hybrid)

		UGCG	RTN3
Description		UDP-glucose ceramide glucosyltransferase	reticulon 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane	Golgi Membrane Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Synapse
	Molecular Function	Protein Binding Ceramide Glucosyltransferase Activity Dihydroceramide Glucosyltransferase Activity	Protein Binding
	Biological Process	Protein Lipidation Glucosylceramide Biosynthetic Process Glycosphingolipid Metabolic Process Epidermis Development Regulation Of Signal Transduction Cell Differentiation Keratinocyte Differentiation Leptin-mediated Signaling Pathway Neuron Development Establishment Of Skin Barrier Intestinal Lipid Absorption Cornified Envelope Assembly	Apoptotic Process Viral Process Vesicle-mediated Transport Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Negative Regulation Of Amyloid-beta Formation
Pathways		Glycosphingolipid metabolism	Synaptic adhesion-like molecules
Drugs		Miglustat Eliglustat
Diseases
GWAS		Benign prostatic hyperplasia ( 30988330) Mean corpuscular hemoglobin ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		3 interacting genes: APP RTN1 RTN3	30 interacting genes: AGTR1 CCR2 CCR8 CDIPT CERT1 DRD2 FGFR1 FHIP1B FXR2 GLP1R GPR152 GPR35 LMNA MITD1 NDRG4 PLEKHF2 PLN PPP2R3C PTPN9 RAB33A RMDN2 RTN4 SACM1L SLC30A3 SLC30A8 SNX1 SPOP TERF1 UGCG ZNF391
Entrez ID		7357	10313
HPRD ID		04190	18516
Ensembl ID		ENSG00000148154	ENSG00000133318
Uniprot IDs		A0A024R157 Q16739	A0A024R5C4 O95197
PDB IDs			7BRU
Enriched GO Terms of Interacting Partners?
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