TNFRSF4 and NUFIP2

Data Source:
BioGRID (unspecified method)

		TNFRSF4	NUFIP2
Description		TNF receptor superfamily member 4	nuclear FMR1 interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Nuclear Body Polysomal Ribosome
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Apolipoprotein B levels ( 32203549) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Heel bone mineral density ( 30598549) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5	100 interacting genes: ADAMTSL4 AMOT COMP CRK CYSRT1 EFEMP2 ESM1 FBLN5 FHL5 FMR1 FUCA2 GRN ICOS KPRP KRT31 KRT37 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE2C LCE2D LGALS13 MDFI MEGF11 MIR1-1 MIR106B MIR107 MIR128-1 MIR128-2 MIR138-2 MIR15B MIR17 MIR18A MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCSK5 PEAR1 PRDX5 RGS17 RGS19 RGS20 STAT3 TNFRSF4 TRAF1 TRIM55 TRIM63 YPEL3 YWHAG
Entrez ID		7293	57532
HPRD ID		02636	11764
Ensembl ID		ENSG00000186827	ENSG00000108256
Uniprot IDs		P43489	Q7Z417
PDB IDs		1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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