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TNFRSF4 and MLLT6
Data Source:
BioGRID
(proximity labelling technology)
TNFRSF4
MLLT6
Description
TNF receptor superfamily member 4
MLLT6, PHD finger containing
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Nucleus
Molecular Function
Virus Receptor Activity
Tumor Necrosis Factor-activated Receptor Activity
Protein Binding
Protein Binding
Nucleosome Binding
Histone Binding
Metal Ion Binding
Biological Process
Positive Regulation Of Immunoglobulin Production
Inflammatory Response
Immune Response
Positive Regulation Of B Cell Proliferation
Tumor Necrosis Factor-mediated Signaling Pathway
T Cell Proliferation
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Viral Entry Into Host Cell
Regulation Of Transcription, DNA-templated
Positive Regulation Of Sodium Ion Transport
Negative Regulation Of Urine Volume
Renal Sodium Excretion
Renal Potassium Excretion
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Histone H3-K79 Methylation
Pathways
TNFs bind their physiological receptors
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Interacting Genes
10 interacting genes:
NUFIP2
RC3H1
SIVA1
TNFRSF9
TNFSF4
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
25 interacting genes:
APP
CASK
CEBPE
CEBPG
CEP44
CREB5
CRX
ENOX2
GRIPAP1
IKBKG
KRTAP10-8
MED15
MEOX2
NSD3
PHC2
PIN1
SPRY2
TCF12
TCF4
TLE5
UBE2G2
UBQLN1
UBQLN4
ZBTB22
ZMYND19
Entrez ID
7293
4302
HPRD ID
02636
08978
Ensembl ID
ENSG00000186827
ENSG00000275023
Uniprot IDs
P43489
P55198
PDB IDs
1D0A
2HEV
2HEY
6OGX
6OKM
6OKN
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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