TNFRSF4 and NAP1L5

Data Source:
HPRD (in vivo)

		TNFRSF4	NAP1L5
Description		TNF receptor superfamily member 4	nucleosome assembly protein 1 like 5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Chromatin Nucleus
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell	Nucleosome Assembly
Pathways		TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Gout ( 30899057) Hair greying ( 26926045) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5	13 interacting genes: ATF4 CEP126 GRB2 HAP1 IKBKG KAT5 LUC7L2 MAGEH1 MTNR1A NAP1L2 PTN SNRPB2 SYCE2
Entrez ID		7293	266812
HPRD ID		02636	17626
Ensembl ID		ENSG00000186827	ENSG00000177432
Uniprot IDs		P43489	Q96NT1
PDB IDs		1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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