TSNAX and BEX3

Data Source:
BioGRID (two hybrid)

		TSNAX	BEX3
Description		translin associated factor X	brain expressed X-linked 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding RNA Binding Endoribonuclease Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Signaling Receptor Binding Nerve Growth Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Identical Protein Binding Metal Ion Binding
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation Production Of SiRNA Involved In RNA Interference RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Multicellular Organism Development Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		Small interfering RNA (siRNA) biogenesis	NADE modulates death signalling
Drugs
Diseases
GWAS		Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: AIMP1 AKAP9 BEX3 BLOC1S5 C1D CARD9 CDK5RAP2 CEP68 CKAP4 COG6 EMILIN1 GADD45G GOLGA3 GPATCH2 GRIPAP1 HMGB2 KCNE4 KLC3 KRT31 LDB2 LDOC1 LZTS2 MRFAP1L1 NSMCE2 NTAQ1 PBXIP1 PMF1 PRPF18 RALYL RFC5 SOGA1 SPRED2 SUN1 SYCE2 SYT17 TCF12 TCP11L1 TSN TSNAXIP1 UBE2I VPS28	41 interacting genes: AIMP2 BFSP2 CACYBP CBY2 CCDC116 CCDC85B CTNNBL1 DIABLO EMILIN1 ENKD1 FSD2 GOLGA8EP GOLGA8F ING4 ING5 KRT34 MCCD1 MDFI MIF MNAT1 NECAB2 NGFR NTRK3 PTPN13 S100A1 S100Z SIVA1 SMARCD1 SMPD1 TACC3 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 TSNAX USHBP1 VTA1 YWHAE ZNF417
Entrez ID		7257	27018
HPRD ID		04270	02291
Ensembl ID		ENSG00000116918	ENSG00000166681
Uniprot IDs		A0A024R3V8 Q99598	Q00994
PDB IDs		3PJA 3QB5	1SA6
Enriched GO Terms of Interacting Partners?
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