Description |
trio Rho guanine nucleotide exchange factor |
protein tyrosine phosphatase receptor type F |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145)
- Antidepressant treatment resistance (number of drugs prescribed) ( 30700811)
- Asthma ( 31959851)
- Asthma (childhood onset) ( 31036433)
- Electroencephalogram traits ( 25387704)
- High density lipoprotein cholesterol levels ( 30498476)
- Intake of total sugars ( 31005972)
- Major depressive disorder ( 27777418)
- Paclitaxel-induced neuropathy ( 23776197)
- Physiological dysregulation (Mahalanobis distance) ( 32235003)
- Waist circumference ( 28552196)
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- Adventurousness ( 30643258)
- Amyotrophic lateral sclerosis (age of onset) ( 22959728)
- anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Attention deficit hyperactivity disorder ( 30478444)
- Attention deficit hyperactivity disorder or cannabis use ( 30610198)
- Autism spectrum disorder or schizophrenia ( 28540026)
- Coffee consumption ( 31046077)
- Cognitive ability (MTAG) ( 29186694)
- Educational attainment ( 27046643)
- General cognitive ability ( 29844566)
- General risk tolerance (MTAG) ( 30643258)
- Household income (MTAG) ( 31844048)
- Intake of total sugars ( 31005972)
- Intelligence (MTAG) ( 29326435)
- Mean reticulocyte volume ( 32888494)
- Refractive error ( 32231278)
- Schizophrenia ( 28991256 25056061 29483656 30285260)
- Smoking initiation ( 30617275)
- Smoking initiation (ever regular vs never regular) ( 30679032)
- Stroke ( 29531354)
- Urate levels ( 31578528)
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Interacting Genes |
13 interacting genes:
BLMH
CDC42
CDC5L
DISC1
EXOC1
FLNA
ITSN2
LIMS1
MAPRE1
PTK2
PTPRF
RAC1
RHOA
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59 interacting genes:
ACAN
ACAT1
ACTB
ARHGEF11
ARHGEF12
ARHGEF2
ATP5F1A
BCAR1
CAV1
CBR1
CDH1
CREBBP
CTNNB1
DEPDC1B
DIAPH1
EEF1A1
EEF1G
FRS2
FYN
GALNT1
GAPDH
GPC4
HSP90AA1
HSPA1A
HSPA1L
HSPA5
HSPA8
HSPA9
INSR
IRS1
IRS2
JUP
LACTB
LCK
LDHA
LDHB
NCAN
NID1
PPFIA1
PPFIA2
PPFIA3
PRPF40A
PTPRA
PTPRD
PTPRZ1
RAP1GDS1
RET
RHOA
ROCK2
SEMG1
SEMG2
SEPTIN9
SKIL
SOWAHC
TRIO
TUBA1B
TUBB4B
VCAN
ZNF512B
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Entrez ID |
7204 |
5792 |
HPRD ID |
03537 |
01552 |
Ensembl ID |
ENSG00000038382
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ENSG00000142949
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Uniprot IDs |
O75962
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G1UI20
P10586
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PDB IDs |
1NTY
2NZ8
6D8Z
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1LAR
2DJU
2DN7
2EDX
2EDY
2YD5
2YD8
4N5U
6KR4
6TPT
6TPU
6TPV
6TPW
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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