TNP2 and PRKACG

Data Source:
BioGRID (enzymatic study)

		TNP2	PRKACG
Description		transition protein 2	protein kinase cAMP-activated catalytic subunit gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Nucleus	Nucleus Nucleoplasm Cytosol Ciliary Base
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	AMP-activated Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Multicellular Organism Development Spermatogenesis Acrosome Reaction Penetration Of Zona Pellucida Positive Regulation Of Protein Processing Spermatogenesis, Exchange Of Chromosomal Proteins	Stimulatory C-type Lectin Receptor Signaling Pathway Renal Water Homeostasis Protein Phosphorylation Spermatogenesis Blood Coagulation Male Gonad Development Protein Kinase A Signaling Activation Of Protein Kinase A Activity High-density Lipoprotein Particle Assembly Cellular Response To Glucagon Stimulus
Pathways			PKA-mediated phosphorylation of CREB PKA-mediated phosphorylation of key metabolic factors Triglyceride catabolism PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins VEGFA-VEGFR2 Pathway CREB1 phosphorylation through the activation of Adenylate Cyclase CREB1 phosphorylation through the activation of Adenylate Cyclase Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state CD209 (DC-SIGN) signaling MAPK6/MAPK4 signaling RET signaling HDL assembly ROBO receptors bind AKAP5 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Asthma ( 31959851) Bulimia nervosa ( 23568457) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Multiple sclerosis ( 22190364) Type 1 diabetes ( 18978792)	Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		17 interacting genes: APPBP2 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 MDFI NOTCH2NLA PRKACA PRKACB PRKACG PRKCA	5 interacting genes: CDK17 CETP HMGN1 TNP1 TNP2
Entrez ID		7142	5568
HPRD ID		01831	01483
Ensembl ID		ENSG00000178279	ENSG00000165059
Uniprot IDs		Q05952 Q4VB56	P22612
PDB IDs
Enriched GO Terms of Interacting Partners?
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