TLE2 and BARHL1

Data Source:
BioGRID (two hybrid)

		TLE2	BARHL1
Description		TLE family member 2, transcriptional corepressor	BarH like homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Transcription Regulator Complex Focal Adhesion Nuclear Body	Chromatin Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Repressing Transcription Factor Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction Animal Organ Morphogenesis Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Beta-catenin-TCF Complex Assembly	Neuron Migration Regulation Of Transcription By RNA Polymerase II Sensory Perception Of Sound Midbrain Development Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of the beta-catenin:TCF transactivating complex NOTCH1 Intracellular Domain Regulates Transcription Deactivation of the beta-catenin transactivating complex Repression of WNT target genes Repression of WNT target genes
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: BARHL1 EMX2 FOXA3 H3-3A HES1 HMGB1 LEF1 MSX1 MSX2 PAX9 PRDM1 RUNX1 TLE1 TLX3 UTY VENTX	2 interacting genes: TLE1 TLE2
Entrez ID		7089	56751
HPRD ID		03025	05554
Ensembl ID		ENSG00000065717	ENSG00000125492
Uniprot IDs		K7EMK7 Q04725	Q9BZE3
PDB IDs
Enriched GO Terms of Interacting Partners?
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