THBS2 and THBS3

Data Source:
HPRD (in vivo, in vitro)

		THBS2	THBS3
Description		thrombospondin 2	thrombospondin 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Platelet Alpha Granule Collagen-containing Extracellular Matrix	Extracellular Region Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Heparin Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Heparin Binding
	Biological Process	Cell Adhesion Negative Regulation Of Angiogenesis	Growth Plate Cartilage Development Cell-matrix Adhesion Ossification Involved In Bone Maturation Bone Trabecula Formation
Pathways		Signaling by PDGF Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Signaling by PDGF
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Blood protein levels ( 30072576 29875488) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Carotid intima media thickness x smoking interaction ( 32117412) Central corneal thickness ( 32528159 29760442) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Copper levels ( 26025379) Dimensional psychopathology (Cognitive) ( 29496196) Joint mobility (Beighton score) ( 27182965) Liver disease severity in Alagille syndrome ( 28090565) Obesity-related traits ( 23251661) Pulse pressure ( 28135244 27841878)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Occipital lobe volume ( 31396565) Serum cancer antigen 15.3 levels ( 31666285) Serum urea levels ( 30808845) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin-to-creatinine ratio ( 26631737) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		3 interacting genes: MMP2 MMP9 THBS3	1 interacting genes: THBS2
Entrez ID		7058	7059
HPRD ID		01766	01767
Ensembl ID		ENSG00000186340	ENSG00000169231
Uniprot IDs		P35442	F5H4Z8 P49746
PDB IDs		1YO8 2RHP
Enriched GO Terms of Interacting Partners?
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