TDO2 and ZFYVE26

Data Source:
BioGRID (two hybrid)

		TDO2	ZFYVE26
Description		tryptophan 2,3-dioxygenase	zinc finger FYVE-type containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Lysosomal Membrane Centrosome Midbody
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Protein Binding Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination Regulation Of Cytokinesis
Pathways		Tryptophan catabolism
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Blood metabolite levels ( 24816252) Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26	35 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20
Entrez ID		6999	23503
HPRD ID		01847	15734
Ensembl ID		ENSG00000151790	ENSG00000072121
Uniprot IDs		P48775	Q68DK2
PDB IDs		4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6VBN
Enriched GO Terms of Interacting Partners?
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