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TRB and CTCF
Data Source:
BioGRID
(pull down, pull down)
TRB
CTCF
Description
T cell receptor beta locus
CCCTC-binding factor
Image
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Alpha-beta T Cell Receptor Complex
Chromosome, Centromeric Region
Condensed Chromosome
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
Signaling Receptor Activity
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Chromatin Insulator Sequence Binding
Sequence-specific DNA Binding
Biological Process
Detection Of Tumor Cell
T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target
Negative Regulation Of Transcription By RNA Polymerase II
DNA Methylation
Regulation Of Gene Expression By Genetic Imprinting
Regulation Of Transcription By RNA Polymerase II
Chromosome Segregation
Negative Regulation Of Cell Population Proliferation
Maintenance Of DNA Methylation
Positive Regulation Of Gene Expression
Nucleosome Positioning
Regulation Of Histone Methylation
Regulation Of Histone Acetylation
Regulation Of Gene Expression, Epigenetic
Regulation Of Molecular Function, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Regulation Of Centromeric Sister Chromatid Cohesion
Protein Localization To Chromosome, Centromeric Region
Genetic Imprinting
Pathways
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS
Narcolepsy (
24204295
)
Elevated fasting plasma glucose (
30004843
)
Eosinophil percentage of white cells (
32888494
)
HDL cholesterol (
19060911
)
Hemoglobin levels (
32327693
)
Refractive error (
32231278
)
Interacting Genes
14 interacting genes:
CD1D
CD247
CD3D
CD3E
CD3G
CTCF
HLA-A
HLA-B
HLA-DRB1
NCOA6
TAF1B
TRA
TRAT1
TRD
21 interacting genes:
CHD1L
CHD7
CHD8
HMGB1
MT-ND4
PARP1
POLR2A
RAD51
RALA
RHOU
RXRA
SIN3A
SMAD3
SMAD4
SUZ12
THRB
TRAF2
TRB
YBX1
ZMYM4
ZMYM6
Entrez ID
6957
10664
HPRD ID
01739
05005
Ensembl ID
ENSG00000102974
Uniprot IDs
A0A2R8YFL0
P49711
PDB IDs
1X6H
2CT1
5K5H
5K5I
5K5J
5K5L
5KKQ
5T00
5T0U
5UND
5YEF
5YEG
5YEH
5YEL
6QNX
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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