Wiki-Pi
About
Search
Browse
People
Updates
Search
BTC and GMPPA
Data Source:
BioGRID
(two hybrid, two hybrid)
BTC
GMPPA
Description
betacellulin
GDP-mannose pyrophosphorylase A
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Integral Component Of Membrane
Clathrin-coated Vesicle Membrane
Cytoplasm
Extracellular Exosome
Molecular Function
Epidermal Growth Factor Receptor Binding
Protein Binding
Growth Factor Activity
Protein Binding
Nucleotidyltransferase Activity
Biological Process
MAPK Cascade
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Urine Volume
ERBB2 Signaling Pathway
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Differentiation
Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Fibroblast Proliferation
Positive Regulation Of Cell Division
Positive Regulation Of Protein Kinase B Signaling
Membrane Organization
Regulation Of Cell Motility
Biosynthetic Process
Pathways
Signaling by ERBB2
Signaling by ERBB4
SHC1 events in ERBB2 signaling
SHC1 events in ERBB2 signaling
PI3K events in ERBB4 signaling
SHC1 events in ERBB4 signaling
Nuclear signaling by ERBB4
PIP3 activates AKT signaling
Signaling by EGFR
GRB2 events in EGFR signaling
GAB1 signalosome
SHC1 events in EGFR signaling
EGFR downregulation
GRB2 events in ERBB2 signaling
PI3K events in ERBB2 signaling
EGFR interacts with phospholipase C-gamma
Constitutive Signaling by Aberrant PI3K in Cancer
Inhibition of Signaling by Overexpressed EGFR
RAF/MAP kinase cascade
ERBB2 Regulates Cell Motility
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
ERBB2 Activates PTK6 Signaling
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Downregulation of ERBB2 signaling
Extra-nuclear estrogen signaling
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Signaling by ERBB2 KD Mutants
Signaling by ERBB2 TMD/JMD mutants
Synthesis of GDP-mannose
Drugs
Diseases
GWAS
Breast size (
27182965
)
Chronic obstructive pulmonary disease (
30804561
)
Diverticular disease (
30177863
)
Electroencephalogram traits (
25387704
)
FEV1 (
30804560
)
Lung function (FEV1/FVC) (
30804560
)
Interacting Genes
11 interacting genes:
DNAJC5
EGFR
ERBB2
ERBB4
GMPPA
KPRP
KRT31
KRTAP1-3
MMP9
SGTA
SGTB
9 interacting genes:
BTC
CDR2
CRP
DCUN1D1
GMPPB
GPKOW
LSM8
NCK1
ZNF688
Entrez ID
685
29926
HPRD ID
02643
13588
Ensembl ID
ENSG00000174808
ENSG00000144591
Uniprot IDs
A0A0S2Z3I5
A0A0S2Z437
P35070
A0A384MDS7
Q96IJ6
PDB IDs
1IOX
1IP0
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?