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SUV39H1 and LNX1
Data Source:
BioGRID
(two hybrid)
SUV39H1
LNX1
Description
suppressor of variegation 3-9 homolog 1
ligand of numb-protein X 1
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Heterochromatin
Condensed Nuclear Chromosome
Nucleus
Nuclear Lamina
Nucleoplasm
Chromatin Silencing Complex
RDNA Heterochromatin
Cytoplasm
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
S-adenosylmethionine-dependent Methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Methyltransferase Activity (H3-K9 Specific)
Protein N-terminus Binding
Ubiquitin-protein Transferase Activity
Protein Binding
PDZ Domain Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
RDNA Heterochromatin Assembly
Chromatin Organization
RRNA Processing
Cellular Response To DNA Damage Stimulus
Cell Cycle
Viral Process
Cell Differentiation
Histone Lysine Methylation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Pathways
PKMTs methylate histone lysines
SIRT1 negatively regulates rRNA expression
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Beard thickness (
26926045
)
Cervical artery dissection (
25420145
)
DNA methylation (variation) (
23725790
)
Heel bone mineral density (
30598549
)
Height (
28552196
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Uterine fibroids (
30194396
31649266
)
Interacting Genes
138 interacting genes:
ATE1
ATF3
ATP6V1B1
BAHD1
BCL11B
C4orf17
C8orf74
CBX1
CBX3
CBX4
CBX5
CDC23
CDCA4
CDCA7L
CEP70
CFAP100
CLK3
CRBN
CREBBP
CRELD2
DBF4B
DCAF8
DDB1
DNMT1
DNMT3A
DNMT3B
DVL3
ELOF1
EP300
ESR1
EZH2
FGD5
FOXR2
FRMD6
FUS
FYN
GOLGA6L9
GPATCH2L
GTF2H2C_2
GTPBP2
H3-3A
H3-4
H3-5
H3C1
H3C15
HDAC1
HDAC2
HDAC3
HDAC5
HOOK2
HOXA1
HOXC4
ID1
ID2
IGFBP4
IL16
ING4
INTS2
KDM1A
KLF15
KLHDC4
KLHL20
KRTAP10-7
KRTAP10-8
LDHAL6B
LENG8
LHX8
LINC02875
LNX1
LOXL4
LZTS2
MALT1
MBD1
MBD4
MCRS1
MSANTD3
MTF2
MTO1
MYOD1
NR1H2
NR1H3
ODAD3
OPA3
PADI6
PHF19
PML
PNKP
PPP1R16A
PRIM2
PRMT6
PSMC1
RASSF1
RASSF2
RB1
RBBP4
RBBP7
RBL1
RBL2
RIN3
RRP8
RSPO2
RUNX1
SBF1
SLFN12
SMAD1
SMAD5
SPATA24
SPRED1
SPSB1
SRGAP3
STX11
STX19
TEKT4
TEX35
THRA
TMEM11
TNFAIP1
TNS2
TRIM41
U2AF1
WDFY3
WIZ
ZBTB2
ZBTB24
ZCCHC17
ZKSCAN5
ZNF165
ZNF417
ZNF436
ZNF438
ZNF451
ZNF557
ZNF581
ZNF649
ZNF670
ZNF829
ZRANB1
ZSCAN9
474 interacting genes:
ABCA1
ABCB1
ABI2
ABR
ACAT2
ACTN1
ACTN3
ACTN4
ACY3
ADAMTSL4
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
ANKS1A
AP1M1
APIP
APOL4
APP
ARF3
ARFIP2
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKB
AURKC
AXIN2
BCR
BEND7
BICD2
BIRC2
BLVRA
BLZF1
BORCS6
BPIFA1
BTBD1
C10orf88
C1QTNF1
CA8
CABP5
CADPS
CALCOCO2
CAMK2N2
CARD9
CASP6
CATSPERD
CBX1
CBY1
CBY2
CCBE1
CCDC102B
CCDC33
CCDC85B
CCDC88B
CCDC91
CCNDBP1
CDA
CDC42EP4
CDIPT
CDKN2D
CEP70
CEP72
CEP76
CEP85
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK1
CLK2
CLK3
CMTM5
COIL
CPNE2
CPSF7
CRACR2B
CRX
CTBP1
CTNND2
CTSO
CUTC
CXADR
CYSLTR2
CYSRT1
DAB1
DAPK1
DCTD
DCTPP1
DCUN1D5
DDIT3
DDX17
DENND1B
DEPTOR
DERL1
DEUP1
DHPS
DMC1
DNPEP
DOCK9
DPF2
DRAP1
DRG1
DTX2
DUSP29
DVL3
DYDC1
DYNLT1
EBF4
EDC3
EEF2KMT
EFEMP2
EFHC2
EGLN3
EHMT2
EIF1AD
EIF4A3
EIF4H
ENOX1
ENOX2
EPHB3
EPM2AIP1
EVI5L
EXOC8
EXOSC1
EXOSC4
EXOSC8
FAM118A
FAM124A
FAM90A1
FAM9B
FASN
FBP1
FBXL12
FHL3
FOXP2
FSD2
FXR1
GAS2L2
GDI1
GIPR
GJD2
GJD4
GLRX3
GMCL1
GMNN
GOLPH3L
GPKOW
GPR142
GRAP2
GRB2
GRIN1
GRIPAP1
GUCD1
HDX
HEXIM2
HIP1
HMBOX1
HMG20A
HNRNPF
HNRNPH1
HOMER3
HOMEZ
HOOK2
HOXA1
HSBP1
HSF2BP
HTR2B
HUNK
IGSF5
IHO1
IKZF3
IL16
IL3RA
ILF3
INKA2
INO80E
INSC
IP6K3
ISCU
JAK3
JOSD1
KALRN
KATNAL2
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KCTD7
KCTD9
KHDRBS2
KHDRBS3
KIAA1328
KIF24
KIFC3
KLHL12
KPRP
KRT15
KRT16
KRTAP1-1
KRTAP10-8
KRTAP12-3
KRTAP13-3
KRTAP2-3
KRTAP2-4
KRTAP4-12
KRTAP4-2
KRTAP5-9
KRTAP6-3
KRTAP9-2
KRTAP9-3
KRTAP9-8
KXD1
LCLAT1
LCP2
LDB2
LDOC1
LEPROTL1
LGALS14
LGR6
LHX2
LNX2
LONRF1
LRRC3B
LRRC73
LSM2
LUZP4
LZTS1
MAD1L1
MAGEA11
MAGEB18
MAPK9
MAPRE2
MEMO1
MEOX2
METTL21A
MID2
MLX
MRFAP1L1
MRPS24
MRPS6
MSANTD4
MSC
MTMR9
MTUS2
MUSTN1
MVB12B
MYEF2
NAB2
NADK
NAGK
NBPF19
NCK2
NDC80
NDOR1
NDUFAB1
NECAB1
NECAB2
NEK6
NKD2
NME1
NME7
NOTCH2NLA
NRCAM
NUDT14
NUMB
NUP37
NUP62
NXT2
ODAD1
ORMDL1
ORMDL3
OSBP2
OSBPL3
OSGIN1
PAFAH1B3
PAICS
PAK5
PBK
PBLD
PCBD1
PDE3B
PDZRN3
PDZRN4
PFDN5
PKDREJ
PKM
PKP4
PLEKHA2
PNMA1
PNMA3
PNMA5
PNMT
POMGNT1
POU6F2
PPIA
PPID
PPIH
PPP1R13B
PQBP1
PRDM14
PRKAR1B
PRKRA
PRMT5
PRPH
PRR13
PRTFDC1
PSMC1
PSME2
PSME3
PSMF1
PTGIR
PTPN11
PTS
PURB
QARS1
RAB33A
RABAC1
RABIF
RAD51D
RAD54B
RALY
RASL11B
RBAK
RBCK1
RBM20
RBMX
RBMY1A1
RBMY1F
RBMY1J
REEP6
RFPL3
RGS20
RIOX2
ROBO3
ROPN1
RPIA
RPS6KA1
RUFY4
RUNDC3A
RUVBL2
S100A3
S100B
SAPCD1
SAT1
SCLT1
SCML1
SCML2
SCNM1
SDK1
SEPTIN1
SGF29
SH2D2A
SHFL
SHTN1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPA
SNRPF
SOCS6
SP4
SPG21
SPHKAP
SRSF1
SRSF3
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
SYCE1L
SYTL2
TACO1
TAX1BP1
TBC1D1
TBCEL
TCF12
TCL1A
TDO2
TEKT4
TGM7
THAP1
THAP7
THG1L
TIFA
TMEM14C
TMEM239
TNFAIP1
TNFAIP3
TNFRSF18
TPM4
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TRIM10
TRIM14
TRIM21
TRIM23
TRIM27
TRIM3
TRIM39
TRIM42
TRIM50
TRIM54
TRIM60
TRIM68
TRIM8
TRIP13
TRIP6
TRMT12
TSC2
TSC22D4
TSG101
TSN
TSPYL2
TSSK3
TYRO3
UBASH3A
UBE2D2
UBE2D4
UBE2N
UBE2V2
UBP1
ULK2
UPP2
USP54
VASN
VCP
VMAC
VPS37B
VPS52
VRK2
WAC
WDR25
WNT8A
WWP1
YWHAZ
ZADH2
ZBED1
ZBTB2
ZBTB24
ZBTB26
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZGPAT
ZNF148
ZNF213
ZNF263
ZNF346
ZNF426
ZNF446
ZNF552
ZNF581
ZNF593
ZNF655
ZRANB1
Entrez ID
6839
84708
HPRD ID
02221
17287
Ensembl ID
ENSG00000101945
ENSG00000072201
Uniprot IDs
O43463
Q8TBB1
PDB IDs
3MTS
3B76
5H7R
5H7S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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