SURF6 and RPL22

Data Source:
BioGRID (two hybrid)

		SURF6	RPL22
Description		surfeit 6	ribosomal protein L22
Image		No pdb structure
GO Annotations	Cellular Component	Granular Component Nucleoplasm Chromosome Nucleolus	Nucleus Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Exosome Presynapse Glutamatergic Synapse Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Heparin Binding Identical Protein Binding Translation Regulator Activity
	Biological Process	Ribosomal Large Subunit Biogenesis Ribosomal Small Subunit Biogenesis	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Alpha-beta T Cell Differentiation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Coagulation factor levels ( 23267103) Epithelial ovarian cancer ( 25134534) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Malaria ( 31844061) Serum alkaline phosphatase levels ( 24094242) Tonsillectomy ( 27182965 28928442) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) TPE interval (resting) ( 32386560)
Interacting Genes		3 interacting genes: CSNK2A1 FAM9B RPL22	23 interacting genes: AP2M1 BAG4 BEND7 CALM1 CDC42 CSE1L CT45A1 DDIT4L DUX4 FGF11 H2BC15 IL7R MAPK14 MDM2 NSFL1C PTEN SDCBP SDCBP2 SRPK2 STAC3 SURF6 THAP1 ZCCHC10
Entrez ID		6838	6146
HPRD ID		01714	01602
Ensembl ID		ENSG00000148296	ENSG00000116251
Uniprot IDs		O75683	P35268
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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