SUPT6H and DNAJB6

Data Source:
BioGRID (two hybrid)

		SUPT6H	DNAJB6
Description		SPT6 homolog, histone chaperone and transcription elongation factor	DnaJ heat shock protein family (Hsp40) member B6
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GO Annotations	Cellular Component	Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Blastocyst Formation Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance	Protein Folding Positive Regulation Of ATPase Activity Regulation Of Protein Localization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Pulse pressure ( 30578418)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		13 interacting genes: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF KRT18 MAP3K1 MLF1 MLF2 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		6830	10049
HPRD ID		03211	07107
Ensembl ID		ENSG00000109111	ENSG00000105993
Uniprot IDs		Q7KZ85	A0A0J9YX62 O75190
PDB IDs		6GME 6GMH 6TED	6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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