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STX5 and STING1
Data Source:
BioGRID
(two hybrid)
STX5
STING1
Description
syntaxin 5
stimulator of interferon response cGAMP interactor 1
Image
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Endomembrane System
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
SNARE Complex
Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Autophagosome Membrane
Nucleoplasm
Mitochondrial Outer Membrane
Endosome
Autophagosome
Peroxisome
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Plasma Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle Membrane
Secretory Granule Membrane
Perinuclear Region Of Cytoplasm
Integral Component Of Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Molecular Function
SNARE Binding
SNAP Receptor Activity
Protein Binding
Cadherin Binding
Protein N-terminus Binding
Protein Binding
Transcription Factor Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Cyclic-di-GMP Binding
Identical Protein Binding
Protein Homodimerization Activity
Cyclic-GMP-AMP Binding
Biological Process
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Vesicle Fusion
Early Endosome To Golgi Transport
Retrograde Transport, Endosome To Golgi
Positive Regulation Of Protein Catabolic Process
COPII Vesicle Coating
Vesicle Docking
Vesicle Fusion With Golgi Apparatus
Golgi Disassembly
Regulation Of Golgi Organization
Autophagosome Assembly
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Viral Process
Positive Regulation Of Macroautophagy
Positive Regulation Of Protein Binding
Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Interferon-beta Production
Cellular Response To Interferon-beta
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Inflammatory Response
Positive Regulation Of DNA-binding Transcription Factor Activity
Protein Complex Oligomerization
Defense Response To Virus
Reticulophagy
Cellular Response To Exogenous DsRNA
Cellular Response To Organic Cyclic Compound
Pathways
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-mediated anterograde transport
Intra-Golgi traffic
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
STING mediated induction of host immune responses
Regulation of innate immune responses to cytosolic DNA
STAT6-mediated induction of chemokines
IRF3-mediated induction of type I IFN
Neutrophil degranulation
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
52 interacting genes:
AARD
APLP1
AQP6
BAG6
BET1
CCDC153
COPS6
CRB3
CREB3L3
EBP
FAM209A
GET3
GOSR1
GOSR2
GPANK1
GPR152
HAP1
HSD17B11
HSD17B13
IMMT
JAGN1
KASH5
LMNA
LNX1
LRIF1
LRRC4C
MAGEA6
MTUS1
NAPA
NAPB
NSFL1C
REEP4
RETREG3
SCFD1
SEC22B
SNAP23
SNAP25
STING1
STX1A
STX2
STX3
STX4
STX8
STXBP1
TACC1
TMEM31
TP53
USO1
VAMP5
VAPB
VCP
VCPIP1
22 interacting genes:
CCDC47
CMTM5
DDOST
IRAK1
LEPROTL1
LTN1
MBOAT7
MUL1
PLLP
REEP6
RNF26
SGPL1
SMIM1
STT3A
STX5
SURF4
TECR
TMEM100
TRIM32
USP20
USP49
YIPF2
Entrez ID
6811
340061
HPRD ID
04426
14173
Ensembl ID
ENSG00000162236
ENSG00000184584
Uniprot IDs
B4DKR0
Q13190
J3QTB1
Q86WV6
V5V0K2
PDB IDs
3EFO
4EF4
4EF5
4EMT
4EMU
4F5D
4F5E
4F5W
4F5Y
4F9E
4F9G
4KSY
4LOH
4LOI
4QXO
4QXP
4QXQ
4QXR
5BQX
5JEJ
6CFF
6CY7
6DNK
6DXG
6DXL
6MX0
6MX3
6MXE
6NT5
6O8B
6O8C
6RM0
6S26
6S27
6S86
6UKM
6UKU
6UKV
6UKW
6UKX
6UKY
6UKZ
6UL0
6XNP
Enriched GO Terms of Interacting Partners
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