SRPRA and RPL10A

Data Source:
BioGRID (two hybrid)

		SRPRA	RPL10A
Description		SRP receptor subunit alpha	ribosomal protein L10a
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GO Annotations	Cellular Component	Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Extracellular Exosome	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Exosome
	Molecular Function	RNA Binding GTPase Activity Signal Recognition Particle Binding GTP Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Protein Targeting Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane IRE1-mediated Unfolded Protein Response Protein Targeting To ER	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of LSU-rRNA Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: RPL10A RUSC2 SSR2	7 interacting genes: ACTB DUX4 PTEN RGS17 SGO1 SRPRA YWHAQ
Entrez ID		6734	4736
HPRD ID		01645	10199
Ensembl ID		ENSG00000182934	ENSG00000198755
Uniprot IDs		P08240	A0A024RCW3 P62906
PDB IDs		2FH5 2GO5 5L3Q 6Y32	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6LQM 6LSR 6LU8 6OLG 6QZP 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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