BPI and ATP6V0B

Data Source:
BioGRID (affinity chromatography technology)

		BPI	ATP6V0B
Description		bactericidal permeability increasing protein	ATPase H+ transporting V0 subunit b
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome	Vacuolar Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Lipopolysaccharide Binding	Transporter Activity Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Antimicrobial Humoral Response Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Macrophage Activation Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		Toll Like Receptor 4 (TLR4) Cascade Neutrophil degranulation Antimicrobial peptides	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Di-Stearoyl-3-Sn-Phosphatidylcholine	Tiludronic acid
Diseases
GWAS		Basophil count ( 32888494) Blood protein levels ( 29875488) Carboplatin disposition in epthelial ovarian cancer ( 29367611) Monocyte percentage of white cells ( 32888494) White blood cell count ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		1 interacting genes: PRSS2	28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG
Entrez ID		671	533
HPRD ID		00174	04759
Ensembl ID		ENSG00000101425	ENSG00000117410
Uniprot IDs		P17213	E9PNL3 Q99437
PDB IDs		1BP1 1EWF
Enriched GO Terms of Interacting Partners?
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