BPI

Description		bactericidal permeability increasing protein
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome
	Molecular Function	Lipopolysaccharide Binding
	Biological Process	Antimicrobial Humoral Response Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Interleukin-6 Production Negative Regulation Of Interleukin-8 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Macrophage Activation Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium
Pathways		Toll Like Receptor 4 (TLR4) Cascade Neutrophil degranulation Antimicrobial peptides
Drugs		Di-Stearoyl-3-Sn-Phosphatidylcholine
Diseases
GWAS		Basophil count ( 32888494) Blood protein levels ( 29875488) Carboplatin disposition in epthelial ovarian cancer ( 29367611) Monocyte percentage of white cells ( 32888494) White blood cell count ( 32888494)
Novel Interacting Genes		1 novel interacting genes: ATP6V0B
Interacting Genes		1 interacting genes: PRSS2
Entrez ID		671
HPRD ID		00174
Ensembl ID		ENSG00000101425
Uniprot IDs		P17213
PDB IDs		1BP1 1EWF
Enriched GO Terms of Interacting Partners?
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