SNTB2 and DGKZ

Data Source:
HPRD (in vitro)

		SNTB2	DGKZ
Description		syntrophin beta 2	diacylglycerol kinase zeta
Image
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Nuclear Speck Lamellipodium Glutamatergic Synapse
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding
	Biological Process		Phosphatidic Acid Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Regulation Of Synaptic Transmission, Glutamatergic Positive Regulation Of 1-phosphatidylinositol-4-phosphate 5-kinase Activity
Pathways			Effects of PIP2 hydrolysis
Drugs			alpha-Tocopherol succinate
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Logical memory (delayed recall) in normal cognition ( 29274321)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)
Interacting Genes		16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN	19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53
Entrez ID		6645	8525
HPRD ID		02491	03260
Ensembl ID		ENSG00000168807	ENSG00000149091
Uniprot IDs		A0A024R732 Q13425	Q13574
PDB IDs		2VRF	5ELQ
Enriched GO Terms of Interacting Partners?
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