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SNRPG and SMN2
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro)
SNRPG
SMN2
Description
small nuclear ribonucleoprotein polypeptide G
survival of motor neuron 2, centromeric
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U5 SnRNP
U7 SnRNP
U1 SnRNP
U2 SnRNP
U4 SnRNP
U12-type Spliceosomal Complex
Cytosol
Small Nuclear Ribonucleoprotein Complex
Methylosome
SMN-Sm Protein Complex
P Granule
U4/U6 X U5 Tri-snRNP Complex
U2-type Prespliceosome
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 2 Spliceosome
Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Spliceosomal Tri-snRNP Complex
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cajal Body
Nuclear Body
Z Disc
Axon
SMN Complex
SMN-Sm Protein Complex
Cytoplasmic Ribonucleoprotein Granule
Neuron Projection
Perikaryon
Gemini Of Coiled Bodies
Molecular Function
RNA Binding
Protein Binding
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
Histone MRNA Metabolic Process
RNA Splicing
Import Into Nucleus
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
DNA-templated Transcription, Termination
Nervous System Development
Import Into Nucleus
Pathways
SLBP independent Processing of Histone Pre-mRNAs
snRNP Assembly
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
RNA Polymerase II Transcription Termination
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
snRNP Assembly
Drugs
Nusinersen
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS
Acne (severe) (
24927181
)
Male-pattern baldness (
28196072
)
Interacting Genes
21 interacting genes:
CEP126
CLNS1A
COPS6
CRMP1
DDIT4L
DDX20
ERG28
FHL3
GDF9
GEMIN5
GEMIN6
IL7R
LSM3
PEA15
SMN2
SNRPD3
SNRPE
SNRPF
TACC1
TCL1B
TLE1
36 interacting genes:
BLOC1S6
BYSL
CHTOP
DDX20
DHX9
EHHADH
FAM9B
FBL
FNDC11
GAR1
GEMIN2
HNRNPUL1
IQUB
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP6-1
KRTAP6-2
MAGED1
POLR1C
POLR2A
PPIG
SMN1
SNRPB
SNRPB2
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
SNU13
SPANXN2
TIAL1
USP9X
VPS28
Entrez ID
6637
6607
HPRD ID
04646
09036
Ensembl ID
ENSG00000143977
ENSG00000205571
Uniprot IDs
C9JVQ0
F5H013
P62308
Q49AN9
B4DP61
E7EQZ4
Q16637
PDB IDs
3CW1
3JCR
3PGW
4F7U
4PJO
4V98
4WZJ
5MQF
5O9Z
5XJC
5XJL
5XJQ
5XJR
5XJT
5XJU
5YZG
5Z56
5Z57
5Z58
6AH0
6AHD
6FF7
6ICZ
6ID0
6ID1
6QDV
6QW6
6QX9
6V4X
6Y53
6Y5Q
7A5P
1G5V
1MHN
2LEH
4A4E
4A4G
4GLI
4QQ6
5XJL
5XJQ
5XJR
5XJS
5XJT
5XJU
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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