SLC13A1 and ASS1

Data Source:
BioGRID (protein complementation assay)

		SLC13A1	ASS1
Description		solute carrier family 13 member 1	argininosuccinate synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber
	Molecular Function	Sodium:sulfate Symporter Activity	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding
	Biological Process	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Zinc Ion Response To Mycotoxin Response To Estradiol Response To Drug Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion
Pathways		Sodium-coupled sulphate, di- and tri-carboxylate transporters	Urea cycle
Drugs			Arginine Aspartic acid Aspartic acid Citrulline Citrulline ATP
Diseases			Citrullinemia (CTLN)
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel) ( 23648065) High density lipoprotein cholesterol levels ( 30498476) Systolic blood pressure ( 30578418)
Interacting Genes		31 interacting genes: ACOT2 ACTR10 APLP2 ARL6IP1 ASS1 CD59 COQ5 COQ9 CRYAB DYNLL1 FTL GRN HSPA1A MKRN1 NDUFS5 OGDHL PDZK1 PNPLA6 PRSS8 RHOA SDHD SEC61A1 SELPLG SERPINA1 SLC9A3R1 SLC9A3R2 TBRG1 TM4SF1 TMED10 TP53I11 TSPAN3	15 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 LINC01554 MLH1 MT2A PTPN1 SLC13A1 SUMO2 TERF1 TERF2 USP4
Entrez ID		6561	445
HPRD ID		08394	04590
Ensembl ID		ENSG00000081800	ENSG00000130707
Uniprot IDs		A4D0X1 Q2NKK0 Q9BZW2	P00966 Q5T6L4
PDB IDs			2NZ2
Enriched GO Terms of Interacting Partners?
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