SLC8A2 and PPP3CB

Data Source:
HPRD (in vivo)

		SLC8A2	PPP3CB
Description		solute carrier family 8 member A2	protein phosphatase 3 catalytic subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Basolateral Plasma Membrane Axon Dendrite Sarcolemma Neuronal Cell Body Dendritic Spine Perikaryon Axon Terminus Synapse Presynapse Postsynapse	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Calcineurin Complex Z Disc T-tubule Glutamatergic Synapse
	Molecular Function	Calcium:sodium Antiporter Activity Calmodulin Binding Sodium Ion Transmembrane Transporter Activity Calcium Ion Transmembrane Transporter Activity Cation:cation Antiporter Activity Metal Ion Binding Calcium:cation Antiporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Enzyme Binding Protein Phosphatase 2B Binding Calmodulin-dependent Protein Phosphatase Activity Protein Dimerization Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Response To Ischemia Ion Transport Cellular Calcium Ion Homeostasis Cell Communication Learning Or Memory Learning Memory Regulation Of Gene Expression Metal Ion Transport Sodium Ion Transmembrane Transport Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization Cognition Regulation Of Cytosolic Calcium Ion Concentration Long-term Synaptic Potentiation Neuron Cellular Homeostasis Calcium Ion Transmembrane Transport Positive Regulation Of Protein Serine/threonine Kinase Activity Calcium Ion Import Across Plasma Membrane Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Action Potential Firing Pattern Regulation Of Calcineurin-mediated Signaling Transport Across Blood-brain Barrier Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane	Negative Regulation Of T Cell Mediated Cytotoxicity Lymphangiogenesis Protein Phosphorylation Protein Dephosphorylation Signal Transduction Wnt Signaling Pathway, Calcium Modulating Pathway Heart Development Learning Memory Dephosphorylation Calcium-ion Regulated Exocytosis T Cell Differentiation Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade Response To Cytokine Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Fc-epsilon Receptor Signaling Pathway T Cell Proliferation T Cell Activation T Cell Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Synaptic Plasticity Axon Extension Regulation Of Insulin Secretion Calcineurin-mediated Signaling Regulation Of Synaptic Vesicle Endocytosis
Pathways		Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Ion homeostasis	DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation ROBO receptors bind AKAP5
Drugs
Diseases
GWAS		Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		7 interacting genes: GPR35 GPR37 PPP3CB YWHAB YWHAE YWHAQ YWHAZ	18 interacting genes: AATK CABIN1 EGFR FBXL17 IRAK1 IRF2 JUN LMTK2 MARCHF7 MYOZ2 MYOZ3 NFATC2 PTK7 ROR2 SLC8A1 SLC8A2 SLC8A3 SOCS3
Entrez ID		6543	5532
HPRD ID		15990	00235
Ensembl ID		ENSG00000118160	ENSG00000107758
Uniprot IDs		Q9UPR5	B7Z781 P16298
PDB IDs			4OR9 4ORA 4ORC
Enriched GO Terms of Interacting Partners?
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